Transient association between proteins elicits alteration of dynamics at sites far away from interfaces

Water at interfaces: from proteins to devices

Behaviour of proteins at interfaces.

The adsorption and conformational changes of three plasma proteins, (bovine) serum albumin, .y-globulin and fibrinogen, on several (bio)polymer surfaces are reported. A theory is developed which invokes reversible adsorption of the proteins in the initial stages and a time dependent conformational change of adsorbed protein leading to essentially irreversible long-term adsorption. In each case ...

Optimal IR: How Far Away?

There exists a gap between what a human user wants in mind and what (s)he could get from the information retrieval (IR) systems by his/her queries. We say an IR system is perfect if it could always provide the users with what they want in their minds if available in corpus, and optimal if it could present to the users what it finds in an optimal way. In this paper, we empirically study how far ...

Chipping Away at P vs NP: How Far Are We from Proving Circuit Size Lower Bounds?

Many people are pessimistic about seeing a resolution to the P vs NP question any time soon. This pessimism extends also to questions about other important complexity classes, including two classes that will be the focus of this talk: TC 0 and NC 1. TC 0 captures the complexity of several important computational problems, such as multiplication, division, and sorting; it consists of all problem...

Nonlinear alteration of transient vergence dynamics after sustained convergence.

BACKGROUND Adaptation models of the horizontal disparity vergence system assume a nonadaptable transient component. They also predict identical postadaptation dynamics during convergence and divergence movements. METHOD To test the adaptation property of the transient component, a set of experiments were performed in which closed-loop vergence dynamics measured before and after sustained conv...